ARMMs: A Non-Viral Delivery Platform for RNA Delivery with Engineerable Tropism
Time: 12:00 pm
day: Day 1
Details:
- Introducing ARRDC1-mediated microvesicle (ARMM) biology and how it can be coopted to generate a non-viral delivery platform for macromolecular therapeutics with excellent prospects for redosability and safety
- Demonstrating how modification of ARRDC1 allows loading of therapeutic RNAs into ARMMs for cellular delivery
- Showcasing how engineering enables alteration of ARMMs surface proteins and fusogens to direct payloads to cells and tissues of therapeutic interest
