LNP & Polymer Delivery of Self-Replicating RNA: Unlocking the Potential of Low Dose RNA Vaccines & Gene Therapy

Time: 9:30 am
day: Day 2

Details:

  • LNP delivery of self-replicating RNA rabies vaccine elicits protective immunity in a majority of healthy participants down to 0.1 microgram (mcg) doses in a prime-boost schedule
  • There were no severe adverse events reported across all doses tested (0.1, 1 and 10 mcg), which supports a massive increase in the therapeutic index achievable with RNA technology in humans
  • Revealing preliminary data on polymer delivery of srRNA for gene therapy applications will be presented

Speakers:

Andrew Geall
Andrew Geall