Stabilization & Enzymatically Gated mRNA Expression Using Nucleic Acid Nanocapsules for Enhancing Endosomal Escape
Time: 4:15 pm
day: Day 1
Details:
• Describing a novel formulation that enables room temperature stabilization of mRNA
• Showcasing how this formulation can target expression of mRNA both in vitro and in vivo using enzyme-gated release mechanisms
• Leveraging how this formulation can be paired with aptamers to enable receptor targeted delivery of mRNA and enhance endosomal escape