RNABL: A Polyester Dendrimer-Based Platform for Therapeutic RNA Delivery

Time: 10:00 am
day: Day 1

Details:

  • RNABL dendrimers are a class of molecularly defined highly branched biodegradable molecules with lower reactogenicity and better safety characteristics
  • RNABL nanoparticles displayed improved characteristics compared to other non-viral nucleic acid delivery platforms tested
  • Structural modifications of RNABL delivery materials resulted in organ-specific nucleic acid delivery (e.g. lungs, spleen, heart)

Speakers: