Uncovering the Pre-Clinical to Clinical Roadmap to Successfully Translate Non-Viral Vehicles for Safe & Efficacious RNA Delivery Leading to Improved Patient Outcomes
Time: 9:05 am
day: Pre-Conference Day
Details:
Being able to translate from the drug concept into an effective drug product can be a huge hurdle due to the difficulty in understanding which preclinical studies and models are robust and relevant for non-viral RNA delivery vehicles. Understanding a successful roadmap for moving through preclinical studies into the clinic is essential to ensure success and better outcomes for patients.
This workshop will address:
- What road map and endpoints are required to successfully transition the vehicle in vitro to in vivo studies?
- How to successfully translate a delivery vehicle from an animal to a human?
- What measures and comparative studies are required to successful translate delivery vehicle vs a drug product?
- How is the field successfully developing representative pre-clinical models for analyzing non-viral delivery vehicles suitable for clinical translatability?
