Mergo®: a Scalable & Programmable Conjugation-Based Delivery System for Short Oligonucleotides
Time: 12:30 pm
day: Day 2
Details:
- Sixfold is overcoming the RNA delivery challenge by systematically screening a large nd diverse conjugate space
- The unique Mergo® system uses modified RNA tags that allow rapid in vivo evaluation of novel modifications that alter biodistribution and cell uptake, and mimic how RNA is naturally shuttled between cells
- Sixfold will further present how the novel unbiased in vivo screening approach they have developed supports computational-based conjugate optimization
